Hematoxicity of amodiaquine in sprague-dawley rats
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چکیده
منابع مشابه
Reproductive and Developmental Toxicity of Amitraz in Sprague-Dawley Rats
The present study was conducted to obtain information on the effects of amitraz on reproductive and developmental parameters in rats. The test chemical was administered via the drinking water containing 0, 40, 120, and 360 ppm to male rats from 2 weeks before mating to the end of 14-day mating period and to females from 2 weeks before mating, throughout mating, gestation and up to lactational d...
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Male Sprague Dawley rats were exposed to 2,3,4,6-tetrachlorophenol (TCP) for 5 days, 2 weeks, 4 weeks, or 13 weeks. TCP was administered by gavage at doses of 0, 10, 25, 50, 100, or 200 mg/kg/day. Endpoints evaluated included clinical observations, body weights, liver weights, serum chemistry, blood TCP, gross pathology, and liver histopathology. There were no TCP exposure-related clinical sign...
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Methacrylonitrile (MeAN) is used in the preparation of plastics, elastomers, homoand copolymers and coatings (Windholz, 1983; Sax and Lewis, 1987) and as a chemical intermediate in the preparation of numerous organic chemicals (Windholz, 1983). MeAN is also used as a replacement for acrylonitrile in the manufacture of carbonated beverage containers (Cosidine, 1974) and is identified as a compon...
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Among organophosphorus pesticides, malathion is considered a relatively safe compound. Malathion, however, functions by inhibiting cholinesterase (ChE) enzymes of the nervous system in both vertebrate and invertebrate organisms. The inactivation of ChE by malathion is therefore a useful indicator of exposure. Because of the increased application of these pesticides, their entry into various env...
متن کاملSubchronic toxicity of vomitoxin in Sprague-Dawley rats.
Purified vomitoxin was incorporated into the diet at a level of 20 ppm and fed to male Sprague-Dawley rats ad lib. for 90 days. Few clinical signs of toxicity were observed. Rats in the vomitoxin treatment group were less efficient in converting feed into body mass, but there was no feed refusal. Terminal body weight was reduced in the vomitoxin treatment group. There were no statistically sign...
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ژورنال
عنوان ژورنال: Toxicology International
سال: 2012
ISSN: 0971-6580
DOI: 10.4103/0971-6580.97197